International Health Regulations


Dr. Arun Mitra

Presentation Overview

Today’s Lecture covers:

  • What is IHR?
  • Why do we need IHR?
  • Historical Evolution
  • Understanding PHEICs

Advanced Topics

  • Active PHEICs Today
  • Core Capacities Framework
  • 2005 vs 2024 Changes
  • Future Implications

What is IHR?

Official Definition


The International Health Regulations are legally binding international law under Article 21 of the WHO Constitution that provide an overarching legal framework for countries to work together to prevent, detect, and respond to public health risks that have the potential for international spread.

– World Health Organization (2016)

Original IHR (1969)

Fundamental Principles


Maximum Security with Minimum Interference


Achieve highest protection against international disease spread while avoiding unnecessary interference with international traffic and trade.

Scope and Application

Biological

Infectious diseases, pandemics

Chemical

Toxic contamination, spills

Radiological

Nuclear accidents

Unknown Origin

Emerging threats

Key Characteristics

  • Disease-Agnostic: Applies regardless of pathogen

  • Event-Based: Focuses on unusual events

  • Risk-Based: Proportional response

  • Evidence-Based: Scientific decisions

  • Rights-Respecting: Protects human dignity

  • Global Coverage: All territories and borders

Why Do We Need IHR?

The Global Health Security Challenge

Our Interconnected World

4.6B

Air passengers annually (2019)

24-48h

Time for global pathogen spread

11B

Tons of goods traded daily

1.4B

International tourist arrivals

Modern Risks

  • Urbanization: 68% in cities by 2050

  • Climate Change: Expanding vectors

  • AMR: 10M deaths by 2050

  • Emerging Pathogens: 75% from animals

  • Bioterrorism: Intentional threats

Risks to Global Health

Risks to Global Health

Historical Impact

  • 1918 Flu: 50-100 million deaths

  • SARS (2003): $100 billion economic impact

  • COVID-19: 7+ million deaths, $28 trillion loss

Historical Evolution of IHR

From Quarantine to Global Health Security

1892-1938 - Multiple Sanitary Conventions

Separate agreements for cholera, plague, yellow fever

1969 - First International Health Regulations

WHO adopts unified regulations for three diseases

2005 - Current IHR Framework

All-hazards approach adopted, enters force 2007

2024 - Major Amendments

Pandemic emergency, equity mechanisms added

What is a PHEIC?

Definition

An extraordinary event which is determined to constitute a public health risk to other States through the international spread of disease and to potentially require a coordinated international response

– World Health Organization (2016)

Four Key Criteria

  1. Extraordinary: Unusual or unexpected event


  1. International Risk : Risk to other countries


  1. Serious Impact: Potential for significant harm


  1. Coordinated Response: Requires international action

New: Pandemic Emergency (2024)

Highest Level of Alert

Important

The 2024 amendments introduced “Pandemic Emergency” as a new, higher level of alert specifically for communicable diseases with pandemic potential (World Health Organization 2024).

Six Criteria for Pandemic Emergency

  1. Wide geographical spread

  2. Overwhelming health systems

  3. Severe social/economic disruption

  4. Need for rapid international action

  5. High morbidity/mortality

  6. Novel or enhanced pathogen

Declaration Process


  1. Detection - Country identifies event

  2. Notification - Report to WHO (24h)

  3. Assessment - WHO evaluation

  4. Emergency Committee - Expert advice

  5. Declaration - Director-General decides

Fukushima Nuclear Disaster

Fukushima Nuclear Disaster

Fukushima Nuclear Disaster

Fukushima Nuclear Disaster

Fukushima Nuclear Disaster

SARS Timeline

COVID Timeline

Contagion

References

World Health Organization. 2016. International Health Regulations (2005): Third Edition. World Health Organization. https://www.who.int/publications/i/item/9789241580496.
World Health Organization. 2024. Amendments to the International Health Regulations (2005). WHA77.17. World Health Organization. https://apps.who.int/gb/ebwha/pdf_files/WHA77/A77_R17-en.pdf.