The International Health Regulations are legally binding international law under Article 21 of the WHO Constitution that provide an overarching legal framework for countries to work together to prevent, detect, and respond to public health risks that have the potential for international spread.
– World Health Organization (2016)
Maximum Security with Minimum Interference
Achieve highest protection against international disease spread while avoiding unnecessary interference with international traffic and trade.
Biological
Infectious diseases, pandemics
Chemical
Toxic contamination, spills
Radiological
Nuclear accidents
Unknown Origin
Emerging threats
Disease-Agnostic: Applies regardless of pathogen
Event-Based: Focuses on unusual events
Risk-Based: Proportional response
Evidence-Based: Scientific decisions
Rights-Respecting: Protects human dignity
Global Coverage: All territories and borders
Our Interconnected World
4.6B
Air passengers annually (2019)
24-48h
Time for global pathogen spread
11B
Tons of goods traded daily
1.4B
International tourist arrivals
Modern Risks
Urbanization: 68% in cities by 2050
Climate Change: Expanding vectors
AMR: 10M deaths by 2050
Emerging Pathogens: 75% from animals
Bioterrorism: Intentional threats
1918 Flu: 50-100 million deaths
SARS (2003): $100 billion economic impact
COVID-19: 7+ million deaths, $28 trillion loss
Separate agreements for cholera, plague, yellow fever
WHO adopts unified regulations for three diseases
All-hazards approach adopted, enters force 2007
Pandemic emergency, equity mechanisms added
An extraordinary event which is determined to constitute a public health risk to other States through the international spread of disease and to potentially require a coordinated international response
– World Health Organization (2016)
Highest Level of Alert
Important
The 2024 amendments introduced “Pandemic Emergency” as a new, higher level of alert specifically for communicable diseases with pandemic potential (World Health Organization 2024).
Wide geographical spread
Overwhelming health systems
Severe social/economic disruption
Need for rapid international action
High morbidity/mortality
Novel or enhanced pathogen
Detection - Country identifies event
Notification - Report to WHO (24h)
Assessment - WHO evaluation
Emergency Committee - Expert advice
Declaration - Director-General decides